Regulation of gonadotropin receptor gene expression.
نویسندگان
چکیده
The receptors for the gonadotropins differ from the other G protein-coupled receptors by having a large extracellular hormone-binding domain, encoded by nine or ten exons. Alternative splicing of the large pre-mRNA of approximately 100 kb can result in mRNA species that encode truncated receptor proteins. In this review we discuss the regulation of gonadotropin receptor mRNA expression and the possible roles of alternative splicing in gonadotropin receptor function.
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ورودعنوان ژورنال:
- Molecular and cellular endocrinology
دوره 100 1-2 شماره
صفحات -
تاریخ انتشار 1994